Menotropin, commonly known as Human Menopausal Gonadotropin (HMG), is a purified preparation containing both luteinizing hormone (LH) and follicle-stimulating hormone (FSH) activity in roughly equal ratios. Originally derived from the urine of postmenopausal women and now also produced via recombinant methods, HMG is widely studied in fertility medicine and hormonal recovery research. It directly stimulates the gonads, making it valuable for protocols targeting both testosterone production and spermatogenesis or follicular development.
HMG provides exogenous LH and FSH, bypassing the hypothalamus and pituitary to act directly on the gonads. In males, LH stimulates Leydig cells in the testes to produce testosterone, while FSH acts on Sertoli cells to support spermatogenesis. In females, FSH drives follicular development in the ovaries while LH supports ovulation and corpus luteum function. Unlike hCG (which mimics LH only) or Kisspeptin (which works upstream at the hypothalamus), HMG delivers the full LH/FSH signal directly to the gonadal tissue, making it particularly relevant for fertility-focused protocols where both hormones are needed.
Frequently paired with hCG in post-cycle recovery research for full LH/FSH coverage Often combined with SERMs (Clomid, Tamoxifen) in HPG axis restoration protocols Pairs with Kisspeptin-10 for upstream and downstream HPG axis support Commonly stacked with aromatase inhibitors to manage estrogen conversion Typical research dosing: 75-150 IU, 2-3 times per week Reconstitute with bacteriostatic water; refrigerate after mixing Use within 2-3 weeks of reconstitution for peptide stability Often used in cycles of 4-12 weeks depending on research protocol
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| Supplier / Lab | Strength / Volume | Price | Availability | |
|---|---|---|---|---|
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UP
UPA Labs
Australia
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75iu
1 Vial
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R390
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In Stock | |
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VM
VMed
South Africa
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75iu
1 Vial
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R820
|
In Stock |