CJC-1295 (DAC)

Growth Hormone Muscle Growth Fat Loss Recovery Anti-Aging IGF-1 Support

1 - 2 x week

Injection (SubQ)

Starting from

R350

2 suppliers available - see pricing tab below

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Dosage

1 - 2 x week

Administration

Injection (SubQ)

Category

Growth Hormone

Overview

CJC-1295 with DAC is a long-acting synthetic analog of growth hormone-releasing hormone (GHRH). The addition of the Drug Affinity Complex (DAC) — a maleimidopropionic acid group that binds to circulating albumin — extends its half-life from minutes to approximately 6-8 days. This produces a sustained elevation of GH and IGF-1 levels, often referred to as a "GH bleed," allowing for convenient weekly dosing. It is the longest-acting GHRH analog available in peptide research and is favored in protocols where consistent GH/IGF-1 elevation is preferred over pulsatile release.

Mechanism of Action

CJC-1295 with DAC binds to GHRH receptors in the anterior pituitary, stimulating the synthesis and release of growth hormone. The DAC modification enables the peptide to covalently bind to serum albumin, protecting it from enzymatic degradation and renal clearance. This results in continuous GHRH receptor activation rather than pulsatile stimulation, producing sustained GH release and elevated IGF-1 levels over the course of days rather than hours. While this differs from the body's natural pulsatile GH pattern, it provides a steady anabolic and lipolytic environment for research applications focused on long-term tissue and metabolic effects.

Key Benefits

Sustained GH and IGF-1 elevation for several days per dose
Convenient 1-2x weekly dosing schedule
Supports lean muscle development and tissue repair
Promotes fat metabolism and improved body composition
Enhances sleep quality and recovery
Supports skin elasticity and anti-aging research
Increases collagen synthesis and connective tissue health
Reduces injection frequency compared to short-acting GHRH analogs

Side Effects & Safety

Injection site redness, swelling, or irritation
Water retention and mild edema, especially in early weeks
Tingling or numbness in hands and feet (carpal tunnel-like symptoms)
Possible joint discomfort due to elevated IGF-1
Increased hunger or altered appetite
Lethargy or fatigue in some research subjects
Disrupts natural pulsatile GH rhythm with prolonged use
Not approved for human use; sold strictly for research purposes
Long-term safety profile in humans has not been fully established
Consult a qualified medical professional before any use

Research & Stacking Notes

Pairs with Ipamorelin or GHRP-2 to amplify GH pulses on top of the sustained baseline Commonly stacked with PEG-MGF or IGF-1 LR3 for muscle growth research Complements BPC-157 and TB-500 in recovery and connective tissue repair protocols Often used in longer research cycles of 8-16 weeks Typical research dosing: 1000-2000 mcg, 1-2 times per week Once-weekly dosing common; twice-weekly preferred for steadier serum levels Less reliant on empty-stomach timing than No DAC version due to sustained release Reconstitute with bacteriostatic water; refrigerate after mixing Use within 4 weeks of reconstitution due to longer protocol cycles

Stacks Well With

CJC-1295 (DAC) (Water not included) (10 vials - 2mg)

Growth Hormone

AOD-9604 (HGH Frag 176-191)

Growth Hormone

Ipamorelin

Growth Hormone

Select your preferred supplier and add to cart. Prices shown include VAT.

Supplier / Lab	Strength / Volume	Price	Availability
HD HD Labs South Africa	2mg 1 Vial	R350	In Stock
UP UPA Labs Australia	2mg 1 Vial	R350	In Stock

All peptides are for research purposes only. Not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional before use.